Laboratory for Study of Behavior and Cognitive Functions
Head: Kateřina Jandová, MD., Ph.D., Vladimír Riljak MD., Ph.D.
Research
The laboratory is focused on the observation of morphological changes and changes in spontaneous behavior of rats during ontogeny and during early adulthood. Several chemical models of epilepsy are under investigation. Spontaneous behavior is monitored in "open field " test – certain kind of arena were the behavior of animals is recorded, observed and classified.
„Open field“ test provided by Metris.
Distribution of locomotor activity of two experimental Wistar rats is depicted above. Rats were monitored for one hour.
Selected publications:
- Riljak V, Marešová D, Pokorný J, Jandová K.: Subconvulsive dose of kainic acid transiently increases the locomotor activity of adult Wistar rats. Physiol Res. 2014 Oct 15. [Epub ahead of print]
- Jandová K, Kozler P, Langmeier M, Marešová D, Pokorný J, Riljak V.: Influence of low-dose neonatal domoic acid on the spontaneous behavior of rats in early adulthood. Physiol Res. 2015 Feb 10;63 Suppl 4:S521-81.
- Kozler P, Riljak V, Jandová K, Pokorný J.: CT imaging and spontaneous behavior analysis after osmotic blood-brain barrier opening in Wistar rat. Physiol Res. 2015 Feb 10;63 Suppl 4:S529-34.
- Schwarz M, Jandová K, Struk I, Marešová D, Pokorný J, Riljak V.: Low dose domoic acid influences spontaneous behavior in adult rats. Physiol Res. 2014;63(3):369-76.
- Jandová K, Marešová D, Pokorný J.: Fast and delayed locomotor response to acute high-dose nicotine administration in adult male rats. Physiol Res. 2013 Dec 12;62 Suppl 1:S81-8.
Grant: PRVOUK P34/LF 1/7